Side effects of hydrochlorothiazide
Skin : effects Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia. Fine SR, Lodha A, hydrochlorothiazide Zoneraich S, Mollura JL "Hydrochlorothiazide-induced acute pulmonary edema." Ann Pharmacother 29 (1995 701-3. Klein MD "Noncardiogenic pulmonary edema following hydrochlorothiazide ingestion." Ann Emerg Med 16 (1987 901-3. You should also avoid sun exposure, as hydrochlorothiazide can increase sun sensitivity. In published placebo-controlled trials comparing.5 mg of hydrochlorothiazide to hydrochlorothiazide 25 mg, effects the.5 mg dose preserved most of the hydrochlorothiazide placebo-corrected blood pressure reduction seen with. Excessive response and hydrochlorothiazide undesirable electrolyte imbalance are less likely to occur with intermittent dosing. Please refer to the hydrochlorothiazide hydrochlorothiazide warnings and precautions sections. Elderly Use A greater blood pressure reduction and an increase in hydrochlorothiazide side effects effects side effects may hydrochlorothiazide be observed in the elderly (i.e. With continued use of hydrochlorothiazide and depletion of sodium, compensatory mechanisms effects tend to increase this exchange and may produce excessive loss of potassium, hydrogen and chloride ions. Nevertheless, periodic determination of serum side electrolytes should be performed in patients who may be at risk for the development of hypokalemia. Hydrochlorothiazide Coupons and Prices Looking to save money on a prescription for Hydrochlorothiazide? Before taking hydrochlorothiazide, tell your doctor or hydrochlorothiazide pharmacist if you hydrochlorothiazide are allergic to it; or side if you have side any other allergies. Magil AB, Ballon HS, Cameron EC, Rae A "Acute interstitial nephritis associated with thiazide side diuretics. You may report side effects to the FDA at 1-800-FDA-1088. Beck ML, Cline JF, Hardman JT, Racela LS, Davis JW "Fatal intravascular immune hemolysis induced by hydrochlorothiazide." Am J effects Clin Pathol 81 (1984 791-4. To prevent hydrochlorothiazide dehydration, drink plenty of fluids unless your doctor directs you otherwise. Contraindications Hydrochlorothiazide is contraindicated in patients with anuria. Usual Adult Dose of Hydrochlorothiazide for Nephrocalcinosis: Initial: 25 mg orally once daily Maintenance dose: May side increase to 50 mg twice daily Usual Adult Dose of Hydrochlorothiazide for Osteoporosis: Initial: 25 mg orally once daily Maintenance dose. Grace AA, Morgan AD, Strickland NH "Hydrochlorothiazide causing unexplained pulmonary oedema." Br J Clin Pract 43 (1989 79-81. Picture of Kidney side Stone Crystal. Distributed By: Watson side Pharma, Inc. Congestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. She was successfully treated with corticosteroids. LaCroix AZ, Ott SM, Ichikawa L, Scholes D, Barlow WE "Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults." Ann Intern Med 133 (2000 516-26 Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances). Lowering Blood Pressure Exercise Tips Pictures Microzide Consumer Information Get emergency medical help if you have signs of an allergic reaction: hives; difficulty side breathing; swelling hydrochlorothiazide of your face, lips, hydrochlorothiazide tongue, or throat. Precautions Electrolyte and Fluid Balance Status In published studies, clinically significant hypokalemia has been consistently less common in patients who received.5 mg of hydrochlorothiazide than in patients who received higher side doses. Frequency not reported : Electrolyte imbalance, hyperglycemia, glycosuria, hyperuricemia, mild hypokalemia (decrease.5 mEq/L) occurs in up to 50 of patients (and may predispose patients to cardiac arrhythmias metabolic alkalosis, hyponatremia, hypomagnesemia, hypercalcemia, hyperglycemia, elevated serum uric acid levels, glucose. An often hydrochlorothiazide side effects hydrochlorothiazide unrecognized problem accompanying chronic medical disorders." Postgrad Med 93 (1993 99-103,. This medication may make you more sensitive to the sun. Pregnancy Teratogenic Effects Pregnancy Category B: Studies in which hydrochlorothiazide was orally administered to pregnant mice effects and rats during side their respective periods of major organogenesis at doses up to 30 mg hydrochlorothiazide/kg, respectively, provided no evidence of harm to the fetus. Holland OB, Kuhnert L, Pollard J, Padia M, Anderson RJ, Blomqvist G "Ventricular ectopic activity with diuretic therapy." Am J Hypertens 1 (1988 380-5. During pregnancy, this medication should be used only when clearly needed. If this edema produces discomfort, increased recumbency will often provide relief. Hair loss (see, hydrochlorothiazide and Hair Loss erectile dysfunction, also referred to as, eD or impotence (see, hydrochlorothiazide Sexual Side Effects ). Specific Side Effects of Hydrochlorothiazide, hydrochlorothiazide has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. When microzide (hydrochlorothiazide capsule) is administered with food, its bioavailability is reduced by 10, the maximum plasma side concentration is reduced by 20, and the time to maximum concentration increases hydrochlorothiazide from.6.9 hours. Sensitivity to the sun, muscle spasm, pancreatitis (inflammation of the pancreas ). Hydrochlorothiazide dosing information Usual Adult Dose of Hydrochlorothiazide for Edema: Usual dose: 25 mg to 100 mg orally once or twice daily Comments: -Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Talk to your pharmacist for more details. Hydrochlorothiazide is the generic side form of the brand-name drug Microzide. Freis ED "The efficacy and safety of diuretics in treating hypertension." side Ann Intern Med 122 (1995 223-6. See a picture of Blood Pressure and learn more about the. Itescu S, Haskell LP, Tannenberg AM "Thiazide-induced clinically significant hypophosphatemia." Clin Nephrol 27 (1987 161-2. This list is not complete. Musculoskeletal : Muscle spasm. Treatment with metoprolol, propranolol and hydrochlorothiazide." Artery 11 (1983. Hydrochlorothiazide is eliminated primarily by renal pathways. Impaired Hepatic Function Thiazides should be used with caution in patients with impaired hepatic function. Febrile Seizures hydrochlorothiazide Febrile seizures, or convulsions caused by fever, can be frightening in small children or infants. Learn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Avoid tanning booths and sunlamps. Garratty G, Houston M, Petz LD, Webb M "Acute immune intravascular hemolysis due to hydrochlorothiazide." Am J Clin Pathol 76 (1981 73-8. Drug interactions, side effects, dosage, and pregnancy and breastfeeding information should be reviewed prior to taking this medication. Pollare T, Lithell H, Berne C "A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension." N Engl J Med 321 (1989. Ref Frequency not reported : Pancreatitis, jaundice (intrahepatic cholestatic jaundice diarrhea, vomiting, sialadenitis, cramping, effects constipation, gastric irritation, nausea, anorexia, acute cholecystitis Ref Although rare, nearly 40 cases of hydrochlorothiazide-induced noncardiogenic pulmonary edema have been reported including at least two fatalities. Kidney failure can occur from an acute event or a chronic condition or disease. The degree to which hydrochlorothiazide is removed by hemodialysis has not been established. Gould L, Reddy CV, Zen B, Singh BK "Life-threatening reaction to thiazides." tate J Med 80 (1980. Hydrochlorothiazide is not expected to be harmful to an unborn baby. Call your doctor at once if you have: a light-headed feeling, like you might pass out; eye pain, vision problems; jaundice (yellowing of the skin or eyes pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum shortness. Cholestyramine and colestipol resins - Cholestyramine and colestipol resins bind the hydrochlorothiazide and reduce its absorption hydrochlorothiazide hydrochlorothiazide from the gastrointestinal tract by up to 85 and 43 percent, respectively. Goodrich AL, Kohn SR "Hydrochlorothiazide-induced lupus erythematosus: a new side variant?" J Am Acad Dermatol 28 (1993. The eruption resolved upon discontinuation of hctz, but she later developed a higher side ANA titer hydrochlorothiazide associated with symptomatic diffuse interstitial pulmonary infiltrates. Treatment varies, but following discontinuation of hydrochlorothiazide most patients respond, with symptoms resolving in a mean.5 days. Most blood pressure lowering medications, including hydrochlorothiazide, are prescribed together with other hypertensive products, along with dietary restrictions, exercise, and, in some cases, weight loss. Ref Frequency not reported : Renal insufficiency (manifest as an increase in serum creatinine and BUN may occur due to hydrochlorothiazide-induced intravascular volume depletion interstitial nephritis, renal failure Ref The incidence of premature ventricular contractions as measured by 48-hour. Krishna GG, Narins RG "Hemodynamic consequences of diuretic-induced hypokalemia." Am J Kidney Dis 12 (1988. Despite its popularity, researchers do not have a clear grasp as to how it works to lower blood pressure. This medicine can pass into breast milk and may harm a nursing baby. Before taking this medicine, you should not use hydrochlorothiazide if you are allergic to it, or if you are unable to urinate. Fager G, Berglund G, Bondjers G, Elmfeldt D, Lager I, Olofsson SO, Smith U, Wiklund O "Effects of anti-hypertensive therapy on serum lipoproteins. Metabolic : Electrolyte imbalance (see precautions hyperglycemia, glycosuria, hyperuricemia. Read about heart disease. You may need to use blood pressure medicine for the rest of your life. Goette DK, Beatrice E "Erythema annulare centrifugum caused by hydrochlorothiazide-induced interstitial nephritis." Int J Dermatol 27 (1988. Other hydrochlorothiazide drugs may interact with hydrochlorothiazide, including prescription and over-the-counter medicines, vitamins, and herbal products. Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn. Hydrochlorothiazide is the second most commonly prescribed antihypertensive in the United States. If you become pregnant, stop taking this medicine and tell your doctor right away. Discuss hydrochlorothiazide the risks and benefits with your doctor. If digitalis has also been administered, hypokalemia may accentuate cardiac arrhythmias. Kasiske BL, Ma JZ, Kalil RS, Louis TA "Effects of antihypertensive therapy on serum lipids." Ann Intern Med 122 (1995 133-41. Call your doctor for medical advice about side effects. Hydrochlorothiazide can lower potassium levels. Fatigue, weakness, these may be symptoms of a condition called hypokalemia or potassium loss. Microzide (hydrochlorothiazide capsule) Capsules side are #4 Teal Opaque/Teal Opaque two piece hard gelatin capsules imprinted with microzide (hydrochlorothiazide capsule) and.5 mg in black ink. Take this quiz and test your IQ of high blood pressure (hypertension effects the cardiovascular disease that causes most strokes and. You shouldn't use hydrochlorothiazide while breastfeeding since it may pass into your breast milk and could harm a nursing baby. Microzide is available hydrochlorothiazide as a generic drug. Keep the bottle tightly closed when not in use. This way, it is possible to see what side effects occurred, how often they occurred, and how they compared to the group not taking the medicine. In rare instances this edema may cause extreme discomfort which is not relieved by rest. High Blood Pressure Treatment (Natural Home Remedies, Diet, Medications) High blood pressure (hypertension) means high pressure (tension) in the arteries. Summary, hydrochlorothiazide (Microzide, Hydrodiuril, hydrochlorothiazide Ezide, effects and Hydro-Par have been discontinued) is a diuretic drug prescribed to treat. Follow your doctor's dosing instructions very carefully. And Microzide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. The following adverse reactions have been reported for doses of hydrochlorothiazide 25 mg and greater and, within each category, are listed in the order of decreasing severity. Chittivelu S "Hydrochlorothiazide-induced pulmonary edema and associated immunologic changes." Ann Pharmacother 33 (1999. Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant.
- Hydrochlorothiazide 25 mg
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- Side effects of hydrochlorothiazide
- Hydrochlorothiazide side effects
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Hydrochlorothiazide side effects
For more information on the possible side effects of hydrochlorothiazide, or tips on how to deal with a side troubling side effect, talk with your doctor or pharmacist. This increases your risk of high levels of lithium in your body, which can cause dangerous side effects. Learn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Magil AB, Ballon HS, Cameron side EC, Rae A "Acute interstitial nephritis associated with thiazide diuretics. Seelig CB "Magnesium deficiency in two hypertensive patient groups." South Med J 83 (1990. It is typically reversible within six months after discontinuation of therapy. Read about high blood. Wagner W, Longerbeam JK, Smith LL, Feikes HL "Drug-induced ulcers of the small bowel causing intestinal obstruction or perforation." Am Surg 33 (1967 7-11. Ref, there have been approximately 34 known cases of thiazide-induced pulmonary edema, side encompassing 52 episodes of pulmonary edema, as of 1991 (per a 1996 review). Ref, frequency not reported : Anaphylactic reactions, necrotizing angiitis ( vasculitis and cutaneous vasculitis respiratory distress (including pneumonitis and pulmonary edema photosensitivity, fever, urticaria, rash, purpura, toxic epidermal necrolysis, ref. Stop using hydrochlorothiazide if you hydrochlorothiazide have: Blurred vision, difficulty reading, eye pain. Kidney Stones (nephrolithiasis) Kidney stones are side solid masses of crystalline material that form in the kidneys. Kidney stones are made of salts and minerals in the urine that stick together, creating small "pebbles" formed within the kidney. There are a variety of liver diseases caused by liver inflammation. You might feel faint or dizzy. Jones IG, Pickens PT "Diabetes mellitus following oral diuretics." Practitioner 199 (1967 209-10. Side Effects of Hydrochlorothiazide Article Continues on Next Page. Call 911 if your symptoms feel life-threatening or if you think hydrochlorothiazide youre having a medical emergency. Grunwald MH, Halevy S, Livni E "Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test." Isr J Med Sci 25 (1989 572-4. Hydrochlorothiazide and Pregnancy Be sure to let your doctor know if you're pregnant or are planning to become pregnant while on hydrochlorothiazide. If youre a senior, you may need a lower dose or a different schedule. Gould L, Reddy CV, Zen B, Singh BK "Life-threatening reaction to thiazides." tate J Med 80 (1980. Smith BL, Tedeschi A, Lane CD "Pancreatitis with a twist." Hosp Pract (Off Ed) 23 (1988 150,. Check with your doctor immediately if any of the following side effects occur: Incidence not known, abdominal or stomach pain back, leg, or stomach pains black, tarry stools bleeding gums blistering, peeling, or loosening of the skin bloating. Taking it again could be fatal (cause hydrochlorothiazide death). Robinson HN, Morison WL, Hood AF "Thiazide diuretic hydrochlorothiazide therapy and chronic effects photosensitivity." Arch Dermatol 121 (1985 522-4. Bring this log with you to your doctor appointments. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. Related Disease Conditions, kidney Failure (Symptoms, Signs, Stages, Causes, Treatment, and Life Expectancy). In some cases, doses as small.5 mg were associated with the development of pulmonary edema. Call your doctor at once if you have: a light-headed feeling, like you might pass out; eye pain, vision problems; jaundice side (yellowing of the skin or eyes pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum shortness. Click on "Free Coupon" below and sign up to get your free SingleCare pharmacy savings card. See a picture of Kidney Stone and learn more about the health topic. Taking corticosteroids with hydrochlorothiazide can cause further loss of electrolytes (especially potassium). This drug may decrease your potassium levels.
Unlike potassium sparing hydrochlorothiazide combination diuretic products, hydrochlorothiazide capsules may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors. More common side effects, the more common side effects that can occur with hydrochlorothiazide include: Also: headache tingling in your hands, legs, and feet. Examples of these drugs hydrochlorothiazide include: angiotensin-converting enzyme (ACE) inhibitors, such as: lisinopril fosinopril enalapril angiotensin receptor blockers (ARBs such as: losartan valsartan hydrochlorothiazide candesartan beta-blockers, such as: atenolol metoprolol bisoprolol calcium channel blockers, such as: amlodipine verapamil diltiazem Cholesterol drugs These drugs. The dose may be increased to 50 mg daily, given as a single or two divided doses. . Thiazides may add to or potentiate the action of other antihypertensive drugs. The dosage per hydrochlorothiazide day shouldnt be more than 100. However, in general, hydrochlorothiazide febrile. That means two things: Research in animals hasnt shown a risk to the fetus when the mother takes hydrochlorothiazide the drug. Serious side effects and their symptoms can include the following: severe skin reactions such as Stevens-Johnson syndrome and exfoliative dermatitis, with symptoms such as: painful skin rash skin peeling and blisters fever mouth sores hydrochlorothiazide kidney failure, with symptoms such as: weakness. Congestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. Indications and Usage for. Hydrochlorothiazide capsules are contraindicated in patients with anuria. Refer to the package insert for lithium preparations before use of such preparations with hydrochlorothiazide. Prerenal kidney failure is caused by blood loss. You should keep a log with the date, time of day, and your blood pressure readings. Hydrochlorothiazide, prices - GoodRx "side_effects_page hydrochlorothiazide. Dependent edema in pregnancy resulting from restriction of venous return by the expanded uterus is properly treated through hydrochlorothiazide elevation of the lower extremities and use of support hydrochlorothiazide hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. It's a prescription diuretic water pill that's used to treat high blood pressure and other conditions. This drug hydrochlorothiazide can cause electrolyte and fluid loss, which may make you produce even less urine. Heart hydrochlorothiazide Disease Quiz: Test Your Medical. Clinical Studies, in an 87 patient 4-week double-blind, placebo controlled, parallel group trial, patients who received hydrochlorothiazide had reductions in seated systolic and diastolic blood pressure that were significantly greater than those seen in patients who received placebo. Overdosage The most common signs and symptoms observed are those caused by electrolyte depletion (hypokalemia, hypochloremia, hyponatremia) and dehydration resulting from excessive diuresis. Hypersensitivity to this product or to other sulfonamide-derived drugs. See a picture of the Heart and learn more. This drug may be used alone. Natriuresis may be accompanied by some loss of potassium and bicarbonate. What is liver disease? Take the Liver Disease Quiz and test your knowledge about this organ and its function. With chronic administration, plasma volume returns hydrochlorothiazide toward normal, but peripheral vascular resistance is decreased. Hydrochlorothiazide, medicare Coverage and Co-Pay Details - GoodRx "price_page ". Dont worry about airport X-ray machines. In these instances, hydrochlorothiazide a short course of diuretic therapy may provide relief and be appropriate. Child dosage (ages 0 to 6 months) The usual dosage is up.5 mg per pound per day, taken by mouth in two divided doses. Travel When traveling with your medication: Always carry your medication with you.